Oxycontin® Oxycodone HCl 30 mg Tablet Bottle 100 Tablets CII

OxyContin Oxycodone OP 30 mg 100 Tablets

December 5, 2025

OxyNorm® 10 mg Oxycodone hydrochloride immediate release 56 hard capsules

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December 5, 2025

Oxycontin® Oxycodone HCl 5 mg Tablet Bottle 100 Tablets CII

OxyContin Oxycodone OP 5 mg 100 Tablets

Name: OxyContin Oxycodone OP 5 mg 100 Tablets
SKU: ATC-Code N02AA55
Availability: InStock

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OxyContin (oxycodone OP) 5 mg tablets are a prolonged/extended-release opioid analgesic used to manage moderate to severe chronic pain when continuous, around-the-clock medication is needed for an extended period. They are a Schedule II controlled substance due to a high potential for abuse and dependence.

Attention Dispenser: Accompanying Medication Guide must be provided to the patient upon dispensing.

ATC-Code N02AA55

OxyContin®
(oxycodone hydrochloride)
extended-release tablets

5 mg

100 Tablets Rx Only

Usual Dosage: Read accompanying prescribing information.
Swallow tablets whole. Do not cut, break, crush, or dissolve.

Dispense in a tight, light-resistant container.
Store at 15°–30°C (59°–86°F).
[See USP Controlled Room Temperature.]

Purdue Pharma L.P.
Stamford, CT 06901-3431
302979-0F

(Barcode: 3 59011 43010 8)

Key Information

Active Ingredient: Each tablet contains 5 mg of oxycodone hydrochloride.
Appearance: The 5 mg prolonged-release tablets are typically light blue, round, and convex, marked with “OC” on one side and “5” on the other (specific markings may vary by manufacturer and region, such as a black imprint ‘5’).
Function: The “OP” designation in some formulations refers to an abuse-deterrent, extended-release version designed to release the medication slowly over 12 hours.
Usage: They are intended for long-term, around-the-clock treatment and are not for “as-needed” or mild pain relief.

Important Safety Information

Swallow Whole: The tablets must be swallowed whole. Breaking, chewing, crushing, or dissolving them is dangerous because it causes the rapid release of the entire dose, which can lead to a potentially fatal overdose.

Addiction and Dependence: Oxycodone can be habit-forming and may cause physical and psychological dependence, even when used as prescribed. Treatment plans should include strategies for safe discontinuation to minimize withdrawal symptoms.

Respiratory Depression: The most significant risk associated with opioids is serious, life-threatening respiratory depression. Close monitoring is essential, especially when starting the medication or increasing the dose.

Storage and Disposal: This medication must be stored securely out of the sight and reach of children. Unused or expired medication should be returned to a pharmacy for safe disposal.

Always consult with a healthcare professional or pharmacist for specific medical advice, dosage instructions, and to address any concerns you may have about this medication.

These statements are for informational purposes only. For medical advice or a diagnosis, you should consult a professional. AI answers may contain errors. Learn more

What are common OxyContin side effects besides pain relief?

Besides pain relief, common side effects of OxyContin (oxycodone ER) typically involvethe central nervous system and gastrointestinal tract. These range from frequent but manageable symptoms to more serious and potentially life-threatening issues.

Very Common Side Effects

The most frequent side effects that often occur in patients (more than 5%) include:

Constipation (the most common overall adverse effect, which often requires management strategies like laxatives)
Nausea and vomiting (these may decrease after a few days as your body adjusts to the medicine)
Drowsiness or somnolence (sleepiness)
Dizziness or lightheadedness
Headache
Sweating
Dry mouth
Itching (pruritus)
Weakness or lack of energy

Serious Side Effects (Require Immediate Medical Attention)

Some side effects can be serious and life-threatening. You should seek emergency help immediately if you experience:

Extreme drowsiness or difficulty waking up/loss of consciousness
Confusion or agitation
Cold, clammy skin
Changes in heart rate (slow heartbeat) or low blood pressure

Long-Term/Other Potential Side Effects

With prolonged use, other effects may develop:

Physical dependence and addiction
Tolerance (needing higher doses to achieve the same effect)
Opioid-induced hyperalgesia (increased sensitivity to pain or pain from normally non-painful stimuli)
Hormonal changes (reduced sex drive, erectile dysfunction, irregular periods, infertility)
Sleep-related breathing problems (sleep apnea)
Adrenal insufficiency (symptoms include nausea, vomiting, loss of appetite, and unusual weakness)

It is important to discuss any side effects with your healthcare provider, as some may be manageable or indicate that a dosage adjustment is necessary.

How do mixed agonist-antagonist opioids interact with full opioid agonists like oxycodone?

Mixed agonist-antagonist opioidsshould generally be avoided in patients who are receiving full opioid agonists like oxycodone . The interaction is complex and can lead to a decrease in the oxycodone’s effectiveness or, more significantly, precipitate acute opioid withdrawal symptoms in patients who are physically dependent on oxycodone.

Mechanism of Interaction

The interaction occurs at the opioid receptors in the brain and nervous system:

Full Agonists (like oxycodone): These drugs bind tightly to the mu-opioid receptors and fully activate them, producing strong pain relief, euphoria, and other typical opioid effects.
Mixed Agonist-Antagonists (like nalbuphine, butorphanol, pentazocine, or the partial agonist buprenorphine): These medications act as agonists (activators) at some opioid receptors (often kappa receptors) and as antagonists (blockers) or partial agonists at the mu-opioid receptors.

When a mixed agonist-antagonist is introduced into a system with a full agonist like oxycodone:

Receptor Competition: The mixed agonist-antagonist has a high affinity for the mu-receptors and effectively displaces the full agonist (oxycodone) from the binding sites.
Reduced Activation: Because the mixed agonist-antagonist only partially activates or completely blocks the mu-receptor, the overall level of receptor activation drops suddenly.
Precipitated Withdrawal: This sudden drop from a state of full activation to partial or no activation is perceived by the body as withdrawal, causing the rapid and intense onset of symptoms such as nausea, vomiting, anxiety, body aches, and sweating.
Reduced Analgesia: The antagonist effect can also simply block the pain-relieving effects of the oxycodone, making the original pain treatment ineffective.

Summary of Risks

Precipitated Opioid Withdrawal: This is the most concerning risk and the primary reason to avoid the combination in opioid-dependent patients.
Unpredictable Analgesia: The combined effect on pain relief is unpredictable and may result in inadequate pain management (a ceiling effect for analgesia with the mixed agent).
Potential for Overdose with Subsequent Dosing: If a patient’s pain relief is blocked by the antagonist effect, they may be tempted to take higher doses of the full agonist, increasing the risk of respiratory depression once the mixed agent wears.

quantity	50 tablets, 100 tablets

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