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Store at 25°C (77°F); excursions permitted to 15°–30°C (59°–86°F)
(See USP Controlled Room Temperature.)
Dispense in tight (USP), child-resistant containers.
NDC 67877-469-90
DOSAGE AND USE:
See accompanying prescribing information.
Each capsule contains 300 mg pregabalin.
Manufactured by:
Pfizer Inc., NY, NY 10017
MADE IN SINGAPORE
Pfizer (logo)
Lyrica® (pregabalin) capsules
C-V
300 mg
ALWAYS DISPENSE WITH MEDICATION GUIDE
90 Capsules
Rx only
Barcode area:
PAA09851
CTN: 0007130119645
20707-1019-68
What conditions is Lyrica prescribed for?
- Fibromyalgia
- Nerve pain (neuropathic pain) associated with:
- Diabetic peripheral neuropathy (nerve pain in the hands or feet caused by diabetes)
- Postherpetic neuralgia (pain after shingles)
- Spinal cord injury
- Partial-onset seizures (a specific type of epilepsy), used in combination with other seizure medications in adults and children as young as one month old.
Mechanism of Action Summary
-
- Binding: By attaching to this specific subunit, pregabalin alters the shape and function of the calcium channels.
- Reduced Calcium Influx: This action decreases the flow (influx) of calcium ions into the nerve terminals.
- Inhibited Neurotransmitter Release: The reduced calcium influx leads to a decrease in the release of several key excitatory neurotransmitters (such as glutamate, norepinephrine, and substance P).
- Signal Dampening: By inhibiting the release of these signaling molecules, pregabalin dampens overactive nerve communication, which helps manage both excessive pain signals and abnormal electrical activity in the brain that causes seizures.
| Quantity | 90 Caps, 100 Caps |
|---|
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